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Comprar Acort (Brand name: Aristocort)

  • €0.82
  • Brand name: Aristocort
  • Disponibilidad: En stock
  • Ingrediente activo: Triamcinolone
Acort es un corticosteroide. Reduce la inflamación y modifica el sistema inmunológico del cuerpo.
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4 mg
Nombre del producto Por píldora Por paquete  
60 píldoras €1.00 €60.16
90 píldoras €0.93 €90.23 €83.27
120 píldoras €0.89 €120.31 €106.39
180 píldoras €0.85 €180.47 €152.63
270 píldoras €0.82 €270.70 €221.98

INDICATIONS

Acort is used for treating a variety of medical conditions, including but not limited to, insufficiency of the adrenal cortex, inflammatory disorders, allergic disorders, and connective tissue disorders. It may also be used for other conditions as determined by your doctor.

INSTRUCTIONS

Use Acort as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Acort by mouth with food.
  • To reduce side effects, take Acort around 8 a.m. in the morning.
  • If you miss a dose of Acort, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Acort.

DOSAGE 

Because of possible physical incompatibilities, Acort (triamcinolone diacetate injectable suspension) should not be diluted or mixed with other solutions.

The initial intramuscular dosage of triamcinolone diacetate injectable suspension may vary from 3 to 48 mg per day depending on the specific disease entity being treated. However, in certain overwhelming, acute, life-threatening situations, administration in dosages exceeding the usual dosages may be justified and may be in multiples of the oral dosages.

STORAGE 

Store Acort at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Acort out of the reach of children and away from pets.

SAFETY INFORMATION

Some medical conditions may interact with Acort. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have or have been recently exposed to a bacterial, fungal, parasitic, ameba, or viral infection, especially measles, chickenpox, shingles, tuberculosis (TB), or herpes simplex of the eye
  • if you have been recently vaccinated, or have had a positive TB skin test
  • if you have heartburn, stomach pain, diarrhea, or intestinal problems (eg, obstructions, perforations, peptic ulcer, recent intestinal surgery)
  • if you have a blood coagulation disorder, heart problems, diabetes mellitus, kidney problems, liver disease, an underactive thyroid, unstable joints, or osteoporosis, fractures, or have had a recent heart attack or joint surgery
  • you have unstable emotions, depression, or myasthenia gravis (muscle weakness)

Some MEDICINES MAY INTERACT with Acort. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Barbiturates (eg, phenobarbital), carbamazepine, hydantoins (eg, phenytoin), or rifampin because they may decrease Acort's effectiveness
  • Clarithromycin, oral contraceptives (birth control pills), or itraconazole because the risk of side effects, such as nervous system or adrenal gland problems, may be increased
  • Aspirin, mifepristone or ritodrine because the risk of their side effects may be increased by Acort

This may not be a complete list of all interactions that may occur. Ask your health care provider if Acort may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Tell your doctor or dentist that you take Acort before you receive any medical or dental care, emergency care, or surgery.
Do not receive a live vaccine (eg, measles, mumps) while you are taking Acort. Talk with your doctor before you receive any vaccine.
Acort may lower the ability of your body to fight infection, especially if you use it for a long period of time. Avoid contact with people who have colds or infections. If you are exposed to chickenpox, measles, or TB while you are taking Acort or during the 12 months after stopping Acort, call your doctor. Tell your doctor if you have an injury or notice signs of infection like fever, sore throat, rash, or chills for up to 12 months after you stop using Acort.
Diabetes patients - Acort may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
Lab tests, including body weight, blood sugar and potassium, or chest x-ray, may be performed while you use Acort. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
Corticosteroids may affect growth rate in CHILDREN and teenagers in some cases. They may need regular growth checks while they take Acort.
Acort should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.


PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Acort while you are pregnant. It is not known if Acort is found in breast milk. Do not breast-feed while taking Acort.

If you are on long-term therapy, you may have WITHDRAWAL symptoms (eg, muscle and joint pain, exhaustion, depression) if you suddenly stop taking Acort. Do not stop taking Acort suddenly or change the dosage without asking your pharmacist or doctor.

SIDE EFFECTS

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

  • Bone fractures;
  • changes in appetite;
  • changes in mood;
  • difficulty sleeping;
  • headache; indigestion;
  • nervousness;
  • stomach bloating;
  • thin, fragile skin 

Seek medical attention right away if any of these SEVERE side effects occur:

  • Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue);
  • black, tarry stools;
  • changes in menstrual periods;
  • convulsions;
  • fast or irregular heartbeat;
  • prolonged sore throat,bcold, or fever; 
  • psychotic behaviors;
  • severe nausea or vomiting;
  • swelling of feet or legs;
  • unusual bruising or bleeding;
  • unusual weight gain;
  • vision problems;
  • vomiting that looks like coffee grounds. 

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider.

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Por favor sigan las recomendaciones de seguridad y las contraindicaciones, las advertencias, al igual que las precauciones ya que estas disminuyen el riesgo de experimentar reacciones no deseadas y efectos secundarios. Pero, aun así, los pacientes hipersensibles a los componentes de la droga, pueden notar reacciones adversas leves y hasta severas, que se enumeraran a continuación. Por favor, póngase en contacto con su médico o un especialista médico en línea para eliminar el riesgo de consecuencias graves. Acuda al médico cuando has notado los siguientes efectos secundarios:

More Common

  • Body aches or pain
  • chills
  • congestion
  • diarrhea
  • dryness or soreness of the throat
  • fever
  • general feeling of discomfort or illness
  • headache
  • hoarseness
  • increased cough
  • joint pain
  • loss of appetite
  • muscle aches and pains
  • nausea
  • runny nose
  • shivering
  • sweating
  • tender, swollen glands in the neck
  • trouble sleeping
  • trouble with swallowing
  • unexplained nosebleeds
  • unusual tiredness or weakness
  • voice changes
  • vomiting

Less Common

  • Cough producing mucus
  • difficulty with breathing
  • noisy breathing
  • shortness of breath
  • tightness in the chest
  • Acid or sour stomach
  • belching
  • heartburn
  • indigestion
  • stomach discomfort, upset, or pain
  • tooth problems
  • upper abdominal or stomach pain

Incidence Not Known

  • Blindness
  • bloody mucus
  • blurred vision
  • changes in vision
  • darkening of the skin
  • decreased vision
  • eye pain
  • fainting
  • fast heartbeat
  • hives
  • irritation
  • itching
  • joint stiffness or swelling
  • loss of appetite
  • lower back or side pain
  • mental depression
  • painful or difficult urination
  • rash
  • redness of the skin
  • slowing of normal growth in children
  • swelling of the eyelids, face, lips, hands, or feet
  • tearing
  • trouble healing
  • white patches in the throat
  • Change in sense of smell or taste
Type Small Molecule
Accession Number DB00620  (APRD00422)
Groups Approved, Vet approved
Synonyms
  • 11β,16α,17α,21-tetrahydroxy-9α-fluoro-1,4-pregnadiene-3,20-dione
  • 9-fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
  • 9α-fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
  • 9α-fluoro-11β,16α,17α,21-tetrahydroxypregna-1,4-diene-3,20-dione
  • 9α-fluoro-16α-hydroxyprednisolone
  • Fluoxyprednisolone
  • Tiamcinolonum
  • Triamcinolona
  • Triamcinolonum
UNII 1ZK20VI6TY
CAS number 124-94-7
Weight Average: 394.4339
Monoisotopic: 394.179166801
Chemical Formula C21H27FO6
InChI
InChI=1S/C21H27FO6/c1-18-6-5-12(24)7-11(18)3-4-13-14-8-15(25)21(28,17(27)10-23)19(14,2)9-16(26)20(13,18)22/h5-7,13-16,23,25-26,28H,3-4,8-10H2,1-2H3/t13-,14-,15+,16-,18-,19-,20-,21-/m0/s1
IUPAC Name
(1R,2S,10S,11S,13R,14S,15S,17S)-1-fluoro-13,14,17-trihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadeca-3,6-dien-5-one
Protein binding

68%

Toxicity

LD50=>500mg/kg (in rats)

Half life

88 minutes

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